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WARNINGS AND PRECAUTIONS

Sildenafil > sildenafil citrate 100mg tablets


Take it as your healthcare provider recommends, which is usually between 30 minutes to four hours before planned sexual activity. Do not take double or extra doses.

Parameter Value Time to Peak Notes
Absorption Rate Rapid, oral administration 30-120 min Depends on food intake
Half-life Approximately 4 hours - Duration of effect
Bioavailability About 40% - Percentage of drug reaching systemic circulation
Metabolism Liver (via CYP3A4 enzyme) - Mainly via hepatic pathways

For this use, take sildenafil as your healthcare provider recommends, which is usually three times a day.

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In particular, make sure that you discuss if you are using any of the following before taking sildenafil. Tell your healthcare provider about all medicines that you take or have recently taken. This may not be a complete list of medicines that can interact with sildenafil. If you or someone else has used too much sildenafil, get medical help right away, call 911, or contact a Poison Control center at 800-222-1222. For this use, sildenafil is used only when needed. If you miss a dose, take it as soon as you remember.

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If it is almost time for your next dose, skip the missed dose and only take the next dose. Ask your healthcare provider if you are unsure what to do after a missed dose.

  • Sildenafil citrate 100mg tablets are FDA-approved for erectile dysfunction.
  • It’s important to adhere to the prescribed timetable to ensure safety.
  • Not suitable for those with severe heart or liver issues without consulting a doctor.
  • Use sildenafil with caution if you have a history of stroke or cardiovascular disease.
  • The medication enhances natural erectile responses, not sexual desire.
  • Avoid grapefruit or grapefruit juice while taking sildenafil due to interactions.
  • Patients should avoid combining sildenafil with recreational drugs.
  • Some users may experience back pain or muscle aches as side effects.
  • Always read the patient information leaflet before use.
  • Report any side effects or unusual symptoms to your healthcare provider.
  • Pregnant or breastfeeding women should avoid using sildenafil.
  • Sildenafil is only effective when sexual stimulation occurs.

This survey is being conducted by the WebMD marketing sciences department.

8.4 Pediatric Use

A household spoon is not an accurate measuring device and may cause you to take the wrong dose. Ask your pharmacist to recommend an appropriate measuring device. Tell your healthcare provider about all of your health conditions and any prescription or sildenafil citrate tablets 50mg over-the-counter (OTC) medicines, vitamins/minerals, herbal products, and other supplements you are using. This will help them determine if sildenafil is right for you. In particular, make sure that you discuss any of the following.

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Tell your healthcare provider if you have any of the following. Heart problems, such as heart rhythm problems, chest pain, or heart failure Heart attack, stroke, or heart surgery within the past six months High blood pressure that is still too high despite taking medicines for it Peyronie's disease, or a penis with an abnormal curve or shape An erection lasting longer than four hours A blood disorder, such as sickle cell anemia An inherited eye disease called retinitis pigmentosa Vision loss, or a problem with the nerve between your eyes and brain (optic nerve) Health conditions or factors that raise the risk of optic nerve problems, such as diabetes, high cholesterol, smoking, being older than 50, or having a “crowded disc,” which is something an eye doctor may see in an eye exam Pulmonary veno-occlusive disease, a condition where blood vessels in the lungs are blocked It is not known if or how sildenafil could affect pregnancy or harm an unborn baby. Tell your healthcare provider if you are or plan to become pregnant. Tell your healthcare provider if you are breastfeeding or plan to breastfeed. Your healthcare provider will advise you if you should take sildenafil while breastfeeding.

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If you take sildenafil after you eat a high-fat meal, such as a burger and fries, it may take longer to start working. Your healthcare provider may recommend limiting or avoiding grapefruit while taking sildenafil. Grapefruit or grapefruit juice can raise sildenafil levels in your body, which can increase the risk of side effects. There are no known interactions between sildenafil and alcohol. Always tell your healthcare provider about any prescription or over-the-counter (OTC) medicines, vitamins/minerals, herbal products, and other supplements you are using. NDC Code(s): 72789-406-15, 72789-406-30, 72789-406-90 If you are a consumer or patient please visit this version.

Point Explanation Importance Tips
Take on an empty stomach Food, especially high-fat meals, may delay effect Ensures quicker onset Preferably take 30-60 minutes before activity
Do not exceed dose Risk of side effects or prolonged erections Safety concern Stick to prescribed dose
Alcohol consumption May reduce efficacy and increase side effects Caution advised Limit alcohol intake during therapy
Report side effects Priapism, vision changes, hearing loss Critical for patient safety Contact healthcare provider immediately

HIGHLIGHTS OF PRESCRIBING INFORMATION These highlights do not include all the information needed to use SILDENAFIL TABLETS safely and effectively.

  • Sildenafil citrate 100mg tablets are used to treat erectile dysfunction temporarily.
  • It is important to confirm the medication dose with a healthcare professional.
  • Store sildenafil in a cool, dry place away from direct sunlight.
  • Take sildenafil exactly as prescribed; do not self-medicate or adjust dose.
  • Always check for possible interactions with other medications before use.
  • Avoid taking sildenafil with fatty foods to ensure faster onset.
  • Patients should report any adverse reactions to their doctor immediately.
  • Men with diabetes need special consultation before using sildenafil.
  • Sildenafil might cause a sensation of dizziness or upset stomach.
  • The medication must be used responsibly to prevent potential dependence.
  • Do not share sildenafil with others; it is prescribed for individual use.
  • Be aware of possible rare side effects like priapism or severe allergic responses.

See full prescribing information for 200mg sildenafil citrate SILDENAFIL TABLETS.SILDENAFIL TABLETS, for oral useInitial U.S. Approval: 1998RECENT MAJOR CHANGESWarnings and Precautions, Effects on the Eye (5.3) 08/2017INDICATIONS AND USAGESildenafil is a phosphodiesterase-5 (PDE5) inhibitor indicated for the treatment of erectile dysfunction (ED) (1)DOSAGE AND ADMINISTRATIONFor most patients, the recommended dose is 50 mg taken, as needed, approximately 1 hour before sexual activity. However, sildenafil tablets may be taken anywhere from 30 minutes to 4 hours before sexual activity ( 2.1)Based on effectiveness and toleration, may increase to a maximum of 100 mg or decrease to 25 mg ( 2.1)Maximum recommended dosing frequency is once per day ( 2.1)DOSAGE FORMS AND STRENGTHSTablets: 25 mg, 50 mg and 100 mg (3)CONTRAINDICATIONSAdministration of sildenafil tablets to patients using nitric oxide donors, such as organic nitrates or organic nitrites in any form. Sildenafil tablets was shown to potentiate the hypotensive effect of nitrates ( 4.1, 7.1, 12.2)Known hypersensitivity to sildenafil or any component of tablet ( 4.2)Administration with guanylate cyclase (GC) stimulators, such as riociguat ( 4.3)WARNINGS AND PRECAUTIONSPatients should not use sildenafil if sexual activity is inadvisable due to cardiovascular status ( 5.1)Patients should seek emergency treatment if an erection lasts >4 hours. Use sildenafil with caution in patients predisposed to priapism ( 5.2)Patients should stop sildenafil tablets and seek medical care if a sudden loss of vision occurs in one or both eyes, which could be a sign of non arteritic anterior ischemic optic neuropathy (NAION). Sildenafil tablets should be used with caution, and only when the anticipated benefits outweigh the risks, in patients with a history of NAION. Patients with a "crowded" optic disc may also be at an increased risk of NAION. ( 5.3)Patients should stop sildenafil tablets and seek prompt medical attention in the event of sudden decrease or loss of hearing ( 5.4)Caution is advised when sildenafil is co-administered with alpha-blockers or anti-hypertensives.

7. Interactions

Sildenafil should not be taken while you are using certain other medicines. Before taking sildenafil, tell your healthcare provider about any prescription or over-the-counter (OTC) medicines, vitamins/minerals, herbal products, and other supplements you are using. See the Interactions section for more details. Do not take sildenafil unless it has been prescribed to you by a healthcare provider. Do not share sildenafil with other people, even if they have the same condition as you.

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Keep sildenafil out of the reach of children. If you keep sildenafil oral liquid in a refrigerator, make sure to keep it away from children who also use the refrigerator. Sexual activity can put extra strain on your heart, which may be unsafe for people with certain health problems, such as a recent heart attack. Talk to your healthcare provider to see if your heart is strong enough for sex. If you feel chest pain, dizziness, or nausea during sex, stop and contact your healthcare provider right away.

Raynaud's phenomenon

Sildenafil does not sildenafil 100 mg cost protect against sexually transmitted infections, including HIV. Sildenafil belongs to a group of medicines, known as phosphodiesterase-5 (PDE-5) inhibitors, which are used to treat erectile dysfunction or pulmonary arterial hypertension. You should not take more than one PDE-5 inhibitor medicine. Medicines in this group include avanafil (Stendra), sildenafil (Viagra, Revatio, and others), tadalafil (Cialis and others), and vardenafil (Levitra, Staxyn). Use an accurate measuring device to measure your dose of sildenafil oral liquid. Concomitant use may lead to hypotension ( 5.5)Decreased blood pressure, syncope, and prolonged erection may occur at higher sildenafil exposures.

  • Sildenafil citrate 100mg tablets are used globally for erectile treatment.
  • The medication’s onset of action is typically within 30-60 minutes.
  • Patients should avoid heavy or greasy foods before taking sildenafil.
  • Do not consume alcohol as it can impair the effectiveness.
  • Sildenafil does not cure erectile dysfunction but helps manage symptoms.
  • Always take medication exactly as your doctor directs.
  • Side effects can include dizziness, flushing, and nasal congestion.
  • Check with your doctor if you are on other medications for safety.
  • The medication is not suitable for patients with eye conditions like retinitis pigmentosa.
  • Use sildenafil responsibly to prevent misuse or adverse health effects.
  • Be aware of and report any persistent pain or changes in vision.
  • Keep all medical appointments to monitor treatment progress.

In patients taking strong CYP inhibitors, such as ritonavir, sildenafil exposure is increased. Decrease in sildenafil dosage is recommended ( 2.4, 5.6)ADVERSE REACTIONSMost common adverse reactions (≥ 2%) include headache, flushing, dyspepsia, abnormal vision, nasal congestion, back pain, myalgia, nausea, dizziness and rash ( 6.1)To report SUSPECTED ADVERSE REACTIONS, contact Nivagen Pharmaceuticals, Inc.

Usual Pediatric Dose for Pulmonary Hypertension

Erection lasting for more than four hours Erection that is unrelated to sexual stimulation Sildenafil can cause mild, temporary vision changes such as seeing a blue tint, abnormal colors, blurry vision, or sensitivity to light. Though rare, some people have reported permanent vision loss. Stop taking sildenafil and get help right away if you have sudden vision loss in one or both eyes. Sudden hearing loss has been reported after taking sildenafil. This may occur along with dizziness and ringing in the ears.

Mechanism of Action

Stop taking sildenafil and get help right away if you have sudden hearing loss or suddenly have trouble hearing as well as usual. Sildenafil may cause a mild and temporary drop in blood pressure. You may be at a higher risk if you have certain health conditions or take blood pressure medicines. If you feel faint or dizzy, lie down. Tell your healthcare provider right away if you have any of the following symptoms of low blood pressure.

A note about sex and gender

You may be at higher risk for this if you take a blood thinner medicine. Tell your healthcare provider if you get nosebleeds often while taking sildenafil. If your nosebleed is severe or will not stop after applying pressure, get help right away. People who are allergic to any of the following should not take sildenafil. Any of the ingredients in the specific product dispensed Your pharmacist can tell you all of the ingredients in the specific sildenafil products they stock. at 1-877-977-0687 or FDA at 1-800-FDA-1088 or INTERACTIONSSildenafil can potentiate the hypotensive effects of nitrates, alpha blockers, and anti-hypertensives ( 4.1, 5.5, 7.1, 7.2, 7.3, 12.2)With concomitant use of alpha blockers, initiate sildenafil at 25 mg dose ( 2.3)CYP3A4 inhibitors (e.g., ritonavir, ketoconazole, itraconazole, erythromycin): Increase sildenafil exposure ( 2.4, 7.4, 12.3) USE IN SPECIFIC POPULATIONSSee 17 for PATIENT COUNSELING INFORMATION and FDA-approved patient labeling.Revised: 6/2023 Warnings and Precautions, Effects on the Eye (5.3) 08/2017 Sildenafil is a phosphodiesterase-5 (PDE5) inhibitor indicated for the treatment of erectile dysfunction (ED) (1) For most patients, the recommended dose is 50 mg taken, as needed, approximately 1 hour before sexual activity.